Volumetric quantification of bone-implant contact using micro-computed tomography analysis based on region-based segmentation
소속 상세정보
:Kang Sung-Won
:Lee Woo-Jin/최순철:Choi Soon-Chul/이삼선:Lee Sam-Sun/허민석:Heo Min-Suk/허경회:Huh Kyung-Hoe/:Kim Tae-Il/:Yi Won-Jin
KMID : 1024020150450010007
Abstract
Purpose : We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA).
Materials and Methods : The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method.
Results : VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05).
Conclusion : It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.
키워드
Absorbable Implants; Osseointegration; X-Ray Microtomography; Computer-Assisted Image Processing
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